SCHEMBL22705683

SCHEMBL22705683

Cn1c2ccccc2c2cccc(-c3cccc4c(-c5cccc6c5C5(c7ccccc7-c7ccccc75)c5ccccc5-6)c5cccc(-c6cccc7c8ccccc8n(C)c67)c5cc34)c21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.42
FTO Q9C0B1 1/20 0.42
HSP90AA1 P07900 1/20 0.39
IDO1 P14902 1/20 0.39
GPR3 P46089 1/20 0.37
KDM4E B2RXH2 5/20 0.33
MAPT P10636 2/20 0.33
NTRK1 P04629 2/20 0.32
HSD17B10 Q99714 3/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
DUSP3 P51452 1/20 0.31
KIF11 P52732 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22706248 0.93 ALKBH5 (0.39) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22705709 0.90 ALKBH5 (0.39) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22705692 0.90 ALKBH5 (0.36) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22707143 0.89 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22705890 0.89 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22707187 0.86 ALKBH5 (0.37) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22707586 0.86 KDM4E (0.32) KDM4EMAPTALDH1A1HPGDMEN1
SCHEMBL22706271 0.86 ALKBH5 (0.35) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22707146 0.86 ALKBH5 (0.39) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL20334569 0.85 ALKBH5 (0.53) ALKBH5FTOHSP90AA1IDO1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed