SCHEMBL22706248

SCHEMBL22706248

Cn1c2ccccc2c2cccc(-c3cccc4c(-c5cccc6c5C(c5ccccc5)(c5ccccc5)c5ccccc5-6)c5cccc(-c6cccc7c8ccccc8n(C)c67)c5cc34)c21

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
HSP90AA1 P07900 1/20 0.36
IDO1 P14902 1/20 0.36
GPR3 P46089 1/20 0.33
HSD17B10 Q99714 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31
APH1A Q96BI3 1/20 0.31
PSENEN Q9NZ42 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705683 0.93 ALKBH5 (0.42) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22705709 0.92 ALKBH5 (0.39) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22706909 0.89 ALKBH5 (0.39) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22706208 0.87 KDM4E (0.30) KDM4EMAPT
SCHEMBL22706251 0.86 GPR3 (0.33) GPR3HSD17B10PSEN1PSEN2APH1B
SCHEMBL22706085 0.86 ALKBH5 (0.36) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22706466 0.86 ALKBH5 (0.36) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22707831 0.85 KDM4E (0.37) KDM4E
SCHEMBL22707143 0.85 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22705890 0.85 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed