SCHEMBL22706018

SCHEMBL22706018

c1ccc([Si]2(c3ccccc3)c3ccccc3-c3cccc(-c4cccc5c(-c6cccc7ccccc67)c6cccc(-c7cccc8c7[Si](c7ccccc7)(c7ccccc7)c7ccccc7-8)c6cc45)c32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALPL P05186 1/20 0.34
GAA P10253 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SOS1 Q07889 1/20 0.33
DHFR P00374 1/20 0.32
TYMP P19971 1/20 0.31
MCL1 Q07820 1/20 0.31
ACMSD Q8TDX5 1/20 0.31
GSK3B P49841 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
AKR1C3 P42330 1/20 0.30
AKR1C2 P52895 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22706721 0.97 GPR84 (0.35) GPR84KDM4EALPLGAAMEN1
SCHEMBL22707680 0.96 GPR84 (0.35) GPR84KDM4EALPLGAAMEN1
SCHEMBL22706722 0.91
SCHEMBL22707079 0.89 ALDH1A1 (0.36) GPR84SOS1ALDH1A1HPGDTSHR
SCHEMBL22706763 0.89 CES1 (0.37) GPR84SOS1ALDH1A1HPGDTSHR
SCHEMBL22706072 0.87 KDM4E (0.32) GPR84KDM4EMEN1KMT2AALDH1A1
SCHEMBL22707903 0.87 GPR84 (0.31) GPR84
SCHEMBL22707192 0.86 GPR84 (0.35) GPR84KDM4EALPLGAAMEN1
SCHEMBL22705930 0.86 ESR1 (0.30)
SCHEMBL22706898 0.84 GPR84 (0.31) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed