SCHEMBL22706144

SCHEMBL22706144

c1ccc2c(-c3c4cccc(-c5ccc6c7ccccc7n7c8ccccc8c5c67)c4cc4c(-c5ccc6c7ccccc7n7c8ccccc8c5c67)cccc34)cccc2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 3/20 0.33
KCNQ2 O43526 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
CASP1 P29466 2/20 0.33
HIF1A Q16665 2/20 0.33
HSD17B10 Q99714 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FLT3 P36888 3/20 0.33
BMX P51813 2/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22707155 0.96 ALDH1A1 (0.34) KCNQ3KCNQ2ALDH1A1HPGDTSHR
SCHEMBL22707534 0.90 CES1 (0.41) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL22706903 0.88 ALDH1A1 (0.34) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL22707570 0.87 HSD17B1 (0.32) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL22706183 0.87 CYP1A2 (0.38) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL22706638 0.86 HSD17B10 (0.34) HSD17B10HSP90AA1IDO1
SCHEMBL22706191 0.85 HSP90AA1 (0.33) ALDH1A1HPGDHSD17B10HSP90AA1IDO1
SCHEMBL20334237 0.85
SCHEMBL22707928 0.84 MAPK14 (0.36) ALDH1A1HPGDHSD17B10HSP90AA1IDO1
SCHEMBL22707154 0.84 ALDH1A1 (0.35) ALDH1A1HPGDTSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed