SCHEMBL22706208

SCHEMBL22706208

c1ccc(C2(c3ccccc3)c3ccccc3-c3cccc(-c4c5cccc(-c6cccc7c8cccc9c%10ccccc%10n(c67)c98)c5cc5c(-c6cccc7c8cccc9c%10ccccc%10n(c67)c98)cccc45)c32)cc1

nearest known ligand 0.30

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22707586 0.93 KDM4E (0.32) KDM4EMEN1MAPTKMT2A
SCHEMBL22706211 0.90
SCHEMBL22706847 0.88 KDM4E (0.30) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22706248 0.87 ALKBH5 (0.39) KDM4EMAPT
SCHEMBL22706207 0.87
SCHEMBL22707831 0.86 KDM4E (0.37) KDM4E
SCHEMBL22707476 0.84 KDM4E (0.32) KDM4EMEN1MAPTKMT2A
SCHEMBL22707812 0.83 KDM4E (0.31) KDM4EMEN1MAPTKMT2A
SCHEMBL22706212 0.83
SCHEMBL22707822 0.82 KDM4E (0.30) KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed