SCHEMBL22706233

SCHEMBL22706233

c1ccc(-c2nc3ccccc3n2-c2c3cccc(-c4cccc5c4oc4ccccc45)c3cc3c(-c4cccc5c4oc4ccccc45)cccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 5/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PIK3CD O00329 1/20 0.40
PIK3CB P42338 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 2/20 0.35
GGPS1 O95749 1/20 0.35
ATM Q13315 1/20 0.35
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
PDE6D O43924 1/20 0.34
ALDH2 P05091 1/20 0.34
ALDH3A1 P30838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15316013 0.86 ESR1 (0.41) ALOX5ESR1ESR2KDM4EALDH1A1
SCHEMBL15316028 0.85 ESR1 (0.39) ALOX5PRKDCESR1ESR2PIK3CD
SCHEMBL15394084 0.85 ESR1 (0.46) ESR1ESR2KDM4EALDH1A1HPGD
SCHEMBL23086801 0.84 RAB9A (0.44) ALOX5PRKDCESR1ESR2PIK3CD
SCHEMBL23169665 0.83 ESR1 (0.46) ALOX5PRKDCESR1ESR2PIK3CD
SCHEMBL30012778 0.83 RAB9A (0.40) ALOX5PRKDCESR1ESR2PIK3CD
SCHEMBL12349671 0.81 ALOX5 (0.43) ALOX5PRKDCESR1ESR2PIK3CD
SCHEMBL1994841 0.81 ESR1 (0.46) ALOX5PRKDCESR1ESR2KDM4E
SCHEMBL12349691 0.81 ESR1 (0.52) ALOX5ESR1ESR2KDM4EALDH1A1
SCHEMBL15394290 0.81 ESR1 (0.47) ALOX5PRKDCESR1ESR2PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed