SCHEMBL22706276

SCHEMBL22706276

Cn1c2ccccc2c2ccc(-c3cccc4c(-c5cccc6c5-c5ccccc5C65c6ccccc6-c6ccc7ccccc7c65)c5cccc(-c6ccc7c8ccccc8n(C)c7c6)c5cc34)cc21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KIF11 P52732 1/20 0.32
GPR3 P46089 1/20 0.31
NTSR1 P30989 1/20 0.31
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22706272 0.94 KDM4E (0.32) L3MBTL1KDM4EALDH1A1MAPTHPGD
SCHEMBL22707210 0.90 RXRA (0.35) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL22707145 0.90 RXRA (0.39) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL22705691 0.88 RXRA (0.35) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL22706460 0.88 RXRA (0.35) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL22706443 0.87 RXRA (0.37) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL22705843 0.87 KDM4E (0.34) L3MBTL1KDM4ENTSR1
SCHEMBL22705679 0.86 RXRA (0.39) RXRARXRBNPC1RAB9AL3MBTL1
SCHEMBL22706271 0.86 ALKBH5 (0.35) GPR3
SCHEMBL22706275 0.86 MAPT (0.30) MAPTGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed