SCHEMBL22706702

SCHEMBL22706702

Cn1c2ccccc2c2cc(-c3cccc4c(-c5ccc6c(-c7ccccc7)cccc6c5)c5cccc(-c6ccc7c(c6)c6ccccc6n7C)c5cc34)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.41
KDM4E B2RXH2 4/20 0.40
GPR3 P46089 1/20 0.39
KMT2A Q03164 4/20 0.39
HPGD P15428 4/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
NTSR1 P30989 1/20 0.37
PSEN1 P49768 1/20 0.37
PSEN2 P49810 1/20 0.37
APH1B Q8WW43 1/20 0.37
NCSTN Q92542 1/20 0.37
APH1A Q96BI3 1/20 0.37
PSENEN Q9NZ42 1/20 0.37
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22706720 0.95 HSD17B10 (0.42) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22706708 0.95 RXRA (0.43) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22706994 0.91 HSD17B10 (0.42) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22706283 0.91 KDM4E (0.39) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22706679 0.90 GPR3 (0.46) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22706539 0.89 KDM4E (0.43) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22707070 0.89 HSD17B10 (0.46) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22707727 0.89 KDM4E (0.44) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22705859 0.87 HSD17B10 (0.44) HSD17B10KDM4EGPR3KMT2AHPGD
SCHEMBL22706906 0.87 HSD17B10 (0.44) HSD17B10KDM4EGPR3KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed