SCHEMBL2270700

SCHEMBL2270700

CC(O)[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.51
ADORA3 P0DMS8 4/20 0.50
PI4KA P42356 2/20 0.49
PI4K2B Q8TCG2 2/20 0.49
PI4K2A Q9BTU6 2/20 0.49
PI4KB Q9UBF8 2/20 0.49
SLC28A1 O00337 2/20 0.49
ADORA1 P30542 2/20 0.49
DPP4 P27487 1/20 0.49
MEN1 O00255 1/20 0.49
MAP3K7 O43318 1/20 0.49
SLC28A2 O43868 1/20 0.49
GAPDH P04406 1/20 0.49
MAPK1 P28482 1/20 0.49
ADORA2B P29275 1/20 0.49
STAT6 P42226 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
DOT1L Q8TEK3 1/20 0.49
SLC29A1 Q99808 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435441 0.92 ADORA3 (0.50) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL29721329 0.92 ADORA3 (0.50) ADORA2AADORA3PI4KAPI4K2BPI4K2A
Benzene SCHEMBL27650186 0.90 PI4KA (0.48) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL6829143 0.89 PI4KA (0.48) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL16112350 0.89 PI4KA (0.47) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL21591025 0.87 ADORA2A (0.49) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL13269464 0.86 PI4KA (0.45) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL30036535 0.86 ADORA3 (0.45) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL5525776 0.86 PI4KA (0.45) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL13268818 0.86 PI4KA (0.45) ADORA2AADORA3PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130302412-A1 Transfer Factor Compositions THE RAMAEKERS FAMILY TRUST 2013-11-14 US disclosed
US-20130122075-A1 ENCAPSULATED TRANSFER FACTOR COMPOSITIONS AND METHODS OF USE THE RAMAEKERS FAMILY TRUST (US) 2013-05-16 US disclosed
US-8008060-B2 Method for growing Cordyceps sinensis on a substrate Aloha Medicinals Inc. (US) 2011-08-30 US disclosed
US-20100221316-A1 Encapsulated Transfer Factor Compositions and Methods of Use RAMAEKERS JOSEPH C 2010-09-02 US disclosed
US-20080299645-A1 Novel method for growing Cordyceps sinensis on a substrate and novel method for hybridizing different strains of Cordyceps sinensis ENTERPRISE BANK & TRUST 2008-12-04 US disclosed
US-7407795-B2 Method for growing Cordyceps sinensis on a substrate and novel method for hybridizing different strains of Cordyceps sinensis Holliday, John (US) 2008-08-05 US disclosed
US-20070204507-A1 Functional substrates for growth of culinary and medicinal mushrooms FUNCTIONAL FUNGI, LLC (US) 2007-09-06 US disclosed
US-20070128253-A1 Encapsulated transfer factor compositions and methods of use RAMAEKERS JOSEPH C 2007-06-07 US disclosed
US-7178285-B2 Functional substrates for growth of culinary and medicinal mushrooms FUNCTIONAL FUNGI, LLC (US) 2007-02-20 US disclosed
EP-1750672-A2 ENCAPSULATED TRANSFER FACTOR COMPOSITIONS AND METHODS OF USE Ramaekers, Joseph D. V. M. C. (US) 2007-02-14 EP disclosed
US-20060073197-A1 Encapsulated transfer factor compositions and methods of use RAMAEKERS JOSEPH C 2006-04-06 US disclosed
US-20060014267-A1 Novel method for growing Cordyceps sinensis on a substrate and novel method for hybridizing different strains of Cordyceps sinensis AMI NEWCO, LLC 2006-01-19 US disclosed
WO-2005112891-A2 ENCAPSULATED TRANSFER FACTOR COMPOSITIONS AND METHODS OF USE RAMAEKERS D V M JOSEPH C (US) 2005-12-01 WO disclosed
US-20050178055-A1 Functional substrates for growth of culinary and medicinal mushrooms DEUTSCHE BANK AG NEW YORK BRANCH, AS ADMINISTRATIVE AGENT. 2005-08-18 US disclosed
WO-2005067581-A2 FUNCTIONAL SUBSTRATES FOR GROWTH OF CULINARY AND MEDICINAL MUSHROOMS FUNCTIONAL FUNGI, LLC (US) 2005-07-28 WO disclosed