Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | PI4KA | P42356 | 3/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.50 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721329 | 1.00 | ADORA3 (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| Benzene SCHEMBL27650186 | 0.98 | PI4KA (0.48) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL2270700 | 0.92 | ADORA2A (0.51) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6935395 | 0.90 | EGFR (0.50) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6829143 | 0.90 | PI4KA (0.48) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL16112350 | 0.89 | PI4KA (0.47) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL27597373 | 0.88 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL31170697 | 0.88 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL13268818 | 0.87 | PI4KA (0.45) | ADORA3ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL5525776 | 0.87 | PI4KA (0.45) | ADORA3ADORA2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| EP-0906574-A4 | METHODS AND KITS FOR THE DETECTION OF ENDOTOXIN | UNIV PENNSYLVANIA (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0799045-B1 | TREATMENT OF HYPEREXCITED NERVE CELL FUNCTIONS | ITEM DEV AB (SE) | 2000-08-16 | — | — | EP | disclosed |
| EP-0906574-A1 | METHODS AND KITS FOR THE DETECTION OF ENDOTOXIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997044665-A9 | METHODS AND KITS FOR THE DETECTION OF ENDOTOXIN | — | 1999-01-21 | — | — | WO | disclosed |
| WO-1997044665-A1 | METHODS AND KITS FOR THE DETECTION OF ENDOTOXIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-11-27 | — | — | WO | disclosed |
| US-5691318-A | NERVOUS SYSTEM DISORDERS AND MEDICAL DIAGNOSIS | ITEM DEVELOPMENT AB | 1997-11-25 | — | — | US | disclosed |
| EP-0799045-A1 | NEW METHOD OF TREATMENT | ITEM DEVELOPMENT AB (SE) | 1997-10-08 | — | — | EP | disclosed |
| US-5565566-A | N6-(ENDO(1R,2S,4S)-2-NORBORNYL)-9-METHYLADENINE OR N6-(ENDO(1S,2R,4R)-2-NORBORNYL)-9-METHYLADENINE | DISCOVERY THERAPEUTICS, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1995029680-A1 | NEW METHOD OF TREATMENT | ITEM DEVELOPMENT AB (SE) | 1995-11-09 | — | — | WO | disclosed |
| EP-0383465-B1 | Tricyclic fused pyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5256398-A | Mixture of adenosine, or an adenosine antagonist, with an adenosine receptor | WHITBY RESEARCH, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0457773-A4 | N?6 -SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | — | 1993-03-10 | — | — | EP | disclosed |
| US-5117830-A | Dilating the vascular system with adenosine; labeling; supplying a adenosine recetor antagonist | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0457773-A1 | N?6 -SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | WHITBY RESEARCH, Inc. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-5032594-A | Adenosine antagonist | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| WO-1990009178-A1 | N6-SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | WHITBY RESEARCH, INC. (US) | 1990-08-23 | — | — | WO | disclosed |
| EP-0383465-A2 | Tricyclic fused pyrimidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-22 | — | — | EP | disclosed |