SCHEMBL22707124

SCHEMBL22707124

Cn1c2ccccc2c2cccc(-c3cccc4c(-c5ccc6c(c5)C(C)(C)c5ccccc5-6)c5cccc(-c6cccc7c8ccccc8n(C)c67)c5cc34)c21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
HSP90AA1 P07900 1/20 0.38
IDO1 P14902 1/20 0.38
GPR3 P46089 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 3/20 0.32
KDM4E B2RXH2 3/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22705850 0.93 ALKBH5 (0.39) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL18565365 0.88 ALKBH5 (0.44) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22708158 0.87 MAPT (0.38) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22708157 0.86 NQO2 (0.34) GPR3L3MBTL1MAPTKDM4EHSD17B10
SCHEMBL22707760 0.86 RXRA (0.40) HSP90AA1IDO1GPR3L3MBTL1MAPT
SCHEMBL22706348 0.86 KDM4E (0.35) L3MBTL1KDM4EKMT2A
SCHEMBL22706085 0.86 ALKBH5 (0.36) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22707709 0.85 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL22705890 0.85 ALKBH5 (0.41) ALKBH5FTOHSP90AA1IDO1GPR3
SCHEMBL13488165 0.82 RXRA (0.40) HSP90AA1IDO1GPR3L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed