SCHEMBL22707142

SCHEMBL22707142

Cn1c2ccccc2c2cc(-c3cccc4c(-c5cccc6c5-c5ccccc5C65c6ccccc6-c6ccccc65)c5cccc(-c6ccc7c(c6)c6ccccc6n7C)c5cc34)ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MEN1 O00255 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GPR3 P46089 1/20 0.37
PSEN1 P49768 2/20 0.35
PSEN2 P49810 2/20 0.35
APH1B Q8WW43 2/20 0.35
NCSTN Q92542 2/20 0.35
APH1A Q96BI3 2/20 0.35
PSENEN Q9NZ42 2/20 0.35
NTRK1 P04629 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22707145 0.93 RXRA (0.39) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22706907 0.92 KDM4E (0.36) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22706441 0.92 KDM4E (0.35) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22707209 0.92 KDM4E (0.33) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22706272 0.90 KDM4E (0.32) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22705681 0.89 GPR3 (0.38) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22706531 0.89 PSEN1 (0.34) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22706459 0.89 KDM4E (0.33) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22707710 0.88 MAPT (0.38) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL22706826 0.86 KDM4E (0.40) KDM4EKMT2AL3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed