SCHEMBL22707255

SCHEMBL22707255

c1ccc2c(c1)Oc1ccccc1C21c2ccccc2-c2c(-c3cccc4c(-c5cc6ccccc6c6ccccc56)c5cccc(-c6cccc7c6-c6ccccc6C76c7ccccc7Oc7ccccc76)c5cc34)cccc21

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GPR84 Q9NQS5 1/20 0.32
CES1 P23141 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22708207 0.90 CES1 (0.38) MAPK1KDM4EATMGPR84CES1
SCHEMBL22708198 0.90 KDM4E (0.36) MAPK1KDM4EATMALDH1A1HPGD
SCHEMBL22707149 0.88 GPR84 (0.31) MAPK1KDM4EATMGPR84
SCHEMBL22707256 0.87 GPR84 (0.33) MAPK1ALDH1A1HPGDTSHRCASP1
SCHEMBL22706266 0.84 GPR84 (0.33) GPR84
SCHEMBL22706267 0.84 GPR84 (0.31) MAPK1KDM4EATMALDH1A1HPGD
SCHEMBL22706851 0.83 KDM4E (0.33) MAPK1KDM4EATMGPR84
SCHEMBL22706043 0.83 GPR84 (0.33) MAPK1KDM4EATMALDH1A1HPGD
SCHEMBL22707592 0.82 GPR84 (0.31) ALDH1A1HPGDHSD17B10GPR84
SCHEMBL22707170 0.82 ALOX5 (0.33) MAPK1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed