Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550676 | 0.78 | ALDH1A1 (0.49) | TSHRATMKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1751661 | 0.76 | KMT2A (0.39) | TSHRATMHSD17B10ALDH1A1GAA | |
| SCHEMBL9989541 | 0.70 | POLB (0.47) | KDM4EALDH1A1GAA | |
| SCHEMBL21765905 | 0.69 | MAPT (0.45) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL14507082 | 0.68 | NR1I2 (0.51) | ALDH1A1GAAAPOBEC3G | |
| SCHEMBL13762630 | 0.68 | CA12 (0.50) | TSHRKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL9272657 | 0.67 | KCNA5 (0.42) | KCNA5KCNH2 | |
| SCHEMBL12888687 | 0.65 | CYP2D6 (0.34) | TSHRKDM4EALDH1A1KCNA5KCNH2 | |
| SCHEMBL1722970 | 0.65 | MAPT (0.39) | EDNRAALDH1A1MAPTNPSR1 | |
| SCHEMBL12889037 | 0.64 | PTPN11 (0.40) | TSHRKDM4EALDH1A1MAPTKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086584-A2 | IMPROVED PROCESS FOR THE PREPARATION OF AMIDE INTERMEDIATES AND THEIR USE THEREOF | MSN LABORATORIES LIMITED (IN) | 2011-07-21 | — | — | WO | disclosed |