SCHEMBL22707484

SCHEMBL22707484

CCc1nc2cccc(-c3c4cccc(-c5ccc6c7ccccc7n7c8ccccc8c5c67)c4cc4c(-c5ccc6c7ccccc7n7c8ccccc8c5c67)cccc34)c2n1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
PDE10A Q9Y233 3/20 0.34
CYP1A2 P05177 1/20 0.33
NQO2 P16083 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
USP2 O75604 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
CRHR1 P34998 2/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22707836 0.84 KDM4E (0.40) ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2
SCHEMBL22706366 0.81 MAPT (0.40) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL22707390 0.80 PDE10A (0.34) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL22707308 0.79 ALDH1A1 (0.42) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL22706359 0.79 KDM4E (0.42) KDM4EL3MBTL1
SCHEMBL22707532 0.78 PDE10A (0.33) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL22707103 0.76 MAPK1 (0.45) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL22706144 0.75 KCNQ3 (0.33) ALDH1A1HPGDMAPK1L3MBTL1HSD17B10
SCHEMBL22707155 0.74 ALDH1A1 (0.34) ALDH1A1MEN1MAPTKMT2AKDM4E
SCHEMBL22706191 0.74 HSP90AA1 (0.33) ALDH1A1MEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200373496-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-11-26 US disclosed