Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746227 | 1.00 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL2270772 | 1.00 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL7746236 | 1.00 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL2270775 | 1.00 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL2885681 | 1.00 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL7746238 | 1.00 | TLR4 (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8488915 | 0.94 | CYP2C9 (0.36) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL1300087 | 0.94 | CYP2C9 (0.36) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10832530 | 0.91 | CYP2C9 (0.35) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10832533 | 0.91 | CYP2C9 (0.35) | TLR4CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| EP-4204515-A1 | AROMATIC ISOTHIOCYANATES | Merck Patent GmbH (DE) | 2023-07-05 | — | — | EP | disclosed |
| CN-116018389-A | Aromatic isothiocyanates | 默克专利股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022043376-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-03-03 | — | — | WO | disclosed |
| CN-113372208-A | Preparation method of trans-4- (trans-4-alkylcyclohexyl) cyclohexanecarboxaldehyde | 山东盛华电子新材料有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-108047015-A | The preparation method of trans -4- substituted cyclohexyls formaldehyde | 烟台德润液晶材料有限公司 | 2018-05-18 | — | — | CN | disclosed |
| EP-2735600-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2018-01-17 | — | — | EP | disclosed |
| CN-107429059-A | ENERGY-SENSITIVE RESIN COMPOSITION | 东京应化工业株式会社 | 2017-12-01 | — | — | CN | disclosed |
| EP-1801186-A1 | Liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-20060198968-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2006-09-07 | — | — | US | disclosed |
| EP-1179522-B1 | Liquid crystalline compound having a difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6544604-B2 | Large dielectric anisotropy and low refractive anisotropy; for driving elements at low voltage | CHISSO CORPORATION (JP) | 2003-04-08 | — | — | US | disclosed |
| US-20020119260-A1 | Liquid crystalline compound having difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | JNC PETROCHEMICAL CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| EP-1179522-A1 | Liquid crystalline compound having a difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0325796-B1 | A LIQUID CRYSTAL COMPOUND AND A MIXTURE CONTAINING THE SAME | Chisso Corporation (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5032312-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-4877548-A | STABLE TO HEAT, LIGHT, ELECTRICITY AND MOISTURE | CHISSO CORPORATION (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0325796-A1 | A liquid crystal compound and a mixture containing the same | Chisso Corporation (JP) | 1989-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | TLR4 680/4885CYP2C9 2000/4885ALDH1A1 1864/4885 |
| US-20020119260-A1 | Liquid crystalline compound having difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | OCIAD2, HCN2, OCIAD1 | TLR4 3890/4885CYP2C9 3802/4885ALDH1A1 2682/4885 |
| US-20060198968-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CCND3, CCND1, TCF12 | TLR4 4241/4885CYP2C9 2535/4885ALDH1A1 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.