SCHEMBL2270952

SCHEMBL2270952

CC1(C)COB(c2cccc3ccccc23)OC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
CYP2A6 P11509 3/20 0.35
HTR1A P08908 2/20 0.35
HTR7 P34969 2/20 0.35
HTR2B P41595 2/20 0.35
TMEM97 Q5BJF2 2/20 0.35
SIGMAR1 Q99720 2/20 0.35
KDM4E B2RXH2 4/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 2/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21879676 0.91 HPRT1 (0.42) ALDH1A1CYP2A6HTR1AHTR7HTR2B
SCHEMBL28499705 0.83 ALDH1A1 (0.37) ALDH1A1CYP2A6HTR1AHTR7HTR2B
SCHEMBL15572626 0.81 JAK2 (0.33)
SCHEMBL17485941 0.81 CYP11B1 (0.39) CYP1A2CYP3A4
SCHEMBL21879641 0.80 TRPM4 (0.35) ALDH1A1CYP2A6KDM4EMAPTMEN1
SCHEMBL30391672 0.80 ALDH1A1 (0.39) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL3199027 0.80 ALDH1A1 (0.39) ALDH1A1CYP2A6HSD17B10TDP1TSHR
SCHEMBL13855305 0.79 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTHSD17B10TDP1
SCHEMBL17940671 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL12370783 0.77 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018146-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS The Procter and Gamble Company (US) 2009-01-28 EP claimed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US claimed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 WO claimed
US-RE49222-E1 Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same DAIKIN INDUSTRIES, LTD. (JP) 2022-09-27 US disclosed
US-9802963-B2 Fluorine-containing complex compound, and production method for fluorine-containing organic compound employing same DAIKIN INDUSTRIES, LTD. (JP) 2017-10-31 US disclosed
US-20160214999-A1 FLUORINE-CONTAINING COMPLEX COMPOUND, AND PRODUCTION METHOD FOR FLUORINE-CONTAINING ORGANIC COMPOUND EMPLOYING SAME DAIKIN INDUSTRIES, LTD. (JP) 2016-07-28 US disclosed
US-8530689-B2 Processes for the preparation of biphenyl compounds THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-09-10 US disclosed
US-8530689-B2 Processes for the preparation of biphenyl compounds THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-09-10 US disclosed
US-8530689-B2 Processes for the preparation of biphenyl compounds THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2013-09-10 US disclosed
US-20110207957-A1 PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2011-08-25 US disclosed
US-20110207957-A1 PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2011-08-25 US disclosed
US-20090144914-A1 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS LIM MU LLL 2009-06-11 US disclosed
US-7507262-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2009-03-24 US disclosed
EP-2018146-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS The Procter and Gamble Company (US) 2009-01-28 EP disclosed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 WO disclosed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US disclosed
US-6344360-B1 INDICATOR WITH BORONATE, ARSENITE, AND/OR GERMANATE GROUP; GLUCOSE DETECTION; MEDICINE, AGRICULTURE SENSORS FOR MEDICINE AND SCIENCE, INC. 2002-02-05 US disclosed
EP-1062516-A1 DETECTION OF ANALYTES BY FLUORESCENT LANTHANIDE CHELATES Sensors for Medicine and Science, Inc. (US) 2000-12-27 EP disclosed
WO-1999046600-A9 DETECTION OF ANALYTES BY FLUORESCENT LANTHANIDE CHELATES SENSORS FOR MED & SCIENCE INC (US) 1999-11-18 WO disclosed
WO-1999046600-A1 DETECTION OF ANALYTES BY FLUORESCENT LANTHANIDE CHELATES SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 1999-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207957-A1 PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS C1S, BAX, C9 ALDH1A1 4182/4885CYP2A6 101/4885HTR1A 1572/4885
US-20090144914-A1 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS KRT18, AKR7A2, AKR1C4 ALDH1A1 205/4885CYP2A6 564/4885HTR1A 4278/4885
US-20160214999-A1 FLUORINE-CONTAINING COMPLEX COMPOUND, AND PRODUCTION METHOD FOR FLUORINE-CONTAINING ORGANIC COMPOUND EMPLOYING SAME AFF1, AFF2, AFF4 ALDH1A1 1452/4885CYP2A6 2624/4885HTR1A 1576/4885
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions KRT18, AKR7A2, AKR1C4 ALDH1A1 205/4885CYP2A6 564/4885HTR1A 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.