SCHEMBL28499705

SCHEMBL28499705

CC1(C)COB(c2cccc3ccccc23)O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
CYP2A6 P11509 2/20 0.37
HTR1A P08908 2/20 0.33
HTR7 P34969 2/20 0.33
HTR2B P41595 2/20 0.33
TMEM97 Q5BJF2 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 3/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
MAPK1 P28482 1/20 0.32
POLB P06746 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
LMNA P02545 1/20 0.30
THRB P10828 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28579068 0.91 HPRT1 (0.40) ALDH1A1CYP2A6HTR1AHTR7HTR2B
SCHEMBL2270952 0.83 ALDH1A1 (0.35) ALDH1A1CYP2A6HTR1AHTR7HTR2B
SCHEMBL28575128 0.81 TRPM4 (0.33) ALDH1A1CYP2A6KDM4EMAPTMEN1
SCHEMBL28546786 0.78 TSHR (0.31) TSHR
SCHEMBL20098739 0.78 MEN1 (0.39) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL29586872 0.78 LPL (0.44) ALDH1A1CYP2A6KDM4EMAPTMEN1
SCHEMBL476862 0.78 LPL (0.44) ALDH1A1CYP2A6KDM4EMAPTMEN1
SCHEMBL22793668 0.77 LPL (0.39) ALDH1A1CYP2A6HTR1AHTR7HTR2B
SCHEMBL29592069 0.77 TAAR1 (0.33) ALDH1A1LMNATSHR
SCHEMBL29592082 0.77 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112047913-A Fluorine-containing complex compound and method for producing fluorine-containing organic compound using same 大金工业株式会社 2020-12-08 CN disclosed
CN-111961068-A Fluorine-containing complex compound and method for producing fluorine-containing organic compound using same 大金工业株式会社 2020-11-20 CN disclosed