SCHEMBL22710100

SCHEMBL22710100

COCCOCCOC[C@@H]1COC(C)(C)O1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.49
TSHR P16473 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
F10 P00742 1/20 0.32
ASGR1 P07306 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9972151 1.00 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL12883057 1.00 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL13248148 1.00 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9972148 0.98 CA2 (0.50) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL31424266 0.98 CA2 (0.50) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9799039 0.98 CA2 (0.50) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL10452650 0.90 CA2 (0.46) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9798886 0.90 CA2 (0.46) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9798873 0.90 CA2 (0.46) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL17461669 0.86 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220411458-A1 TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING Roche Sequencing Solutions, Inc. 2022-12-29 US disclosed
WO-2020236526-A1 TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING STRATOS GENOMICS, INC. (US) 2020-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411458-A1 TRANSLOCATION CONTROL ELEMENTS, REPORTER CODES, AND FURTHER MEANS FOR TRANSLOCATION CONTROL FOR USE IN NANOPORE SEQUENCING PHAX, DNTT, NSUN3 CA2 3854/4885TSHR 2942/4885SMN1; SMN2 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.