SCHEMBL9972148

SCHEMBL9972148

COCCOCC1COC(C)(C)O1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
F10 P00742 1/20 0.33
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799039 1.00 CA2 (0.50) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL31424266 1.00 CA2 (0.50) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL12883057 0.98 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL22710100 0.98 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL13248148 0.98 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9972151 0.98 CA2 (0.49) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9798873 0.92 CA2 (0.46) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL9798886 0.92 CA2 (0.46) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL10452650 0.92 CA2 (0.46) CA2TSHRSMN1; SMN2ALDH1A1TDP1
SCHEMBL7875753 0.85 CA2 (0.59) CA2TSHRSMN1; SMN2ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2104716-B1 TINTED CLEAR COATINGS UV STABILIZED WITH 2-HYDROXY PHENYL TRIAZINE BASF SE (DE) 2018-02-21 EP disclosed
US-20150079412-A1 TINTED CLEAR COATINGS UV STABILIZED WITH 2-HYDROXY PHENYL TRIAZINE BASF SE (DE) 2015-03-19 US disclosed
US-8895068-B2 Nanoparticle composition and associated methods thereof GENERAL ELECTRIC COMPANY (US) 2014-11-25 US disclosed
US-8889103-B2 Diagnostic agent composition and associated methods thereof GENERAL ELECTRIC COMPANY (US) 2014-11-18 US disclosed
US-8262945-B2 Stabilization of photochromic systems BASF SE (DE) 2012-09-11 US disclosed
US-20120156141-A1 NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF GENERAL ELECTRIC COMPANY (US) 2012-06-21 US disclosed
US-20120156142-A1 DIAGNOSTIC AGENT COMPOSITION AND ASSOCIATED METHODS THEREOF GENERAL ELECTRIC COMPANY (US) 2012-06-21 US disclosed
US-7771709-B2 Polyethersiloxane copolymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
US-20100119858-A1 TINTED CLEAR COATINGS FOR WOOD CIBA CORPORATION (US) 2010-05-13 US disclosed
US-20100062270-A1 TINTED CLEAR COATINGS UV STABILIZED WITH 2-HYDROXY PHENYL TRIAZINE CIBA CORPORATION (US) 2010-03-11 US disclosed
US-20090289236-A1 STABILIZATION OF PHOTOCHROMIC SYSTEMS DESTRO MARA 2009-11-26 US disclosed
US-7288583-B2 Method of content protection with durable UV absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-10-30 US disclosed
US-7214742-B2 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks CIBA SPECIALTY CHEMICALS CORP. (US) 2007-05-08 US disclosed
US-20070064195-A1 Stabilization of photochromic systems CIBA CORPORATION 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120156142-A1 DIAGNOSTIC AGENT COMPOSITION AND ASSOCIATED METHODS THEREOF PHOSPHO1, PHAX, PIK3CA CA2 1362/4885TSHR 2562/4885SMN1; SMN2 1720/4885
US-20120156141-A1 NANOPARTICLE COMPOSITION AND ASSOCIATED METHODS THEREOF PHOSPHO1, PIK3CA, PTEN CA2 2456/4885TSHR 3625/4885SMN1; SMN2 3395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.