Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | GPR6 | P46095 | 11/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271430 | 0.93 | CXCR3 (0.48) | CXCR3GRM5GPR6MEN1KMT2A | |
| SCHEMBL2269616 | 0.91 | CXCR3 (0.65) | CXCR3GPR6USP30MEN1KMT2A | |
| SCHEMBL2268315 | 0.84 | CXCR3 (0.57) | CXCR3GRM5MEN1KMT2ABTK | |
| SCHEMBL2270608 | 0.84 | CXCR3 (0.57) | CXCR3GRM5MEN1KMT2ABTK | |
| SCHEMBL2267846 | 0.84 | CXCR3 (0.54) | CXCR3GRM5MEN1KMT2ABTK | |
| SCHEMBL2362900 | 0.84 | CCR2 (0.46) | GPR6BTK | |
| SCHEMBL2221638 | 0.82 | CXCR3 (0.78) | CXCR3GRM5USP30MEN1KMT2A | |
| SCHEMBL2223197 | 0.81 | CXCR3 (0.48) | CXCR3GRM5MEN1KMT2ABTK | |
| SCHEMBL2264590 | 0.79 | CXCR3 (0.53) | CXCR3GPR6MEN1KMT2A | |
| SCHEMBL2269437 | 0.79 | CXCR3 (0.48) | CXCR3GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084985-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-14 | — | — | WO | disclosed |