SCHEMBL2271015

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2271260	0.92	CXCR3 (0.48)	CXCR3ATMRAB9AMEN1KMT2A
	SCHEMBL2269654	0.91	CXCR3 (0.48)	CXCR3ATMMEN1KMT2AF10
	SCHEMBL2269698	0.91	CXCR3 (0.49)	CXCR3ATMMEN1KMT2AMAPK1
	SCHEMBL2354024	0.90	CXCR3 (0.48)	CXCR3ATMRAB9AMEN1KMT2A
	SCHEMBL16448963	0.89	CXCR3 (0.47)	CXCR3ATMMEN1KMT2AUSP2
	SCHEMBL2275511	0.89	CXCR3 (0.49)	CXCR3ATMRAB9AALDH1A1LMNA
	SCHEMBL2270555	0.89	CXCR3 (0.47)	CXCR3ATMRAB9AMEN1KMT2A
	SCHEMBL2270467	0.88	ALDH1A1 (0.47)	CXCR3ATMKMT2AALDH1A1ACKR3
	SCHEMBL2276600	0.88	CXCR3 (0.49)	CXCR3ATMRAB9AMEN1KMT2A
	SCHEMBL2221634	0.87	CXCR3 (0.52)	CXCR3ATMMEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.