Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16414519 | 0.78 | — | — | |
| SCHEMBL15352943 | 0.73 | — | — | |
| SCHEMBL22799817 | 0.69 | — | — | |
| SCHEMBL22692957 | 0.69 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL5447840 | 0.69 | — | — | |
| SCHEMBL99567 | 0.69 | ACHE (0.34) | ALDH1A1 | |
| SCHEMBL273282 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNATACR2L3MBTL1 | |
| SCHEMBL5883815 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNATACR2L3MBTL1 | |
| SCHEMBL22426578 | 0.67 | ELANE (0.33) | ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL12422 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384189-A | Positive electrode lithium supplementing additive, preparation method thereof, lithium supplementing layer, positive electrode plate and lithium ion battery | 江苏蓝固新能源科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-111655685-B | Thiophene derivative and use thereof | 藤本株式会社 | 2023-11-17 | — | — | CN | disclosed |
| EP-3744719-B1 | THIOPHENE DERIVATIVE AND USE THEREOF | FUJIMOTO CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| CN-115108959-B | Photobleachable visible light initiator containing benzylidene ketone structure, and preparation method and application thereof | 武汉大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-115108959-A | Photobleachable visible light initiator containing benzylidene ketone structure and preparation method and application thereof | 武汉大学 | 2022-09-27 | — | — | CN | disclosed |
| US-20210061795-A1 | THIOPHENE DERIVATIVE AND USE THEREOF | FUJIMOTO CO., LTD. (JP) | 2021-03-04 | — | — | US | disclosed |
| EP-3744719-A1 | THIOPHENE DERIVATIVE AND USE THEREOF | Fujimoto Co., Ltd. (JP) | 2020-12-02 | — | — | EP | disclosed |
| CN-111655685-A | Thiophene derivative and use thereof | 藤本株式会社 | 2020-09-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061795-A1 | THIOPHENE DERIVATIVE AND USE THEREOF | TNF, TPMT, CD47 | ALDH1A1 226/4885KDM4E 530/4885LMNA 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.