SCHEMBL22711577

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19493728	0.94	CYP3A4 (0.50)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL18053449	0.93	CYP3A4 (0.57)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL18106823	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL18106835	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL18106838	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL10960758	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL18106831	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL18106818	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL11186720	0.86	CYP3A4 (0.73)	CYP3A4NPSR1ADORA2BUSP2KMT2A
	SCHEMBL16658922	0.86	LMNA (0.39)	NPSR1ADORA2BKMT2AGAAADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.