Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RGS4 | P49798 | 1/20 | 0.37 |
| ▸ | RGS8 | P57771 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23509686 | 0.92 | RGS4 (0.44) | LMNAALDH1A1RGS4RGS8ADORA2B | |
| SCHEMBL16658929 | 0.92 | RGS4 (0.44) | LMNAALDH1A1RGS4RGS8MAOA | |
| SCHEMBL22711577 | 0.86 | CYP3A4 (0.53) | ALDH1A1MAOAMAOBADORA2BADORA2A | |
| SCHEMBL24999154 | 0.83 | — | — | |
| SCHEMBL23509687 | 0.82 | MAOA (0.36) | MAOAMAOB | |
| SCHEMBL14802479 | 0.80 | ALDH1A1 (0.52) | LMNAALDH1A1ADORA2BPDE2AADORA2A | |
| SCHEMBL25283306 | 0.80 | RGS4 (0.34) | RGS4RGS8 | |
| SCHEMBL19493728 | 0.79 | CYP3A4 (0.50) | ALDH1A1MAOAMAOBADORA2BADORA2A | |
| SCHEMBL18053449 | 0.77 | CYP3A4 (0.57) | ALDH1A1CNOT7ADORA2BADORA2ANPSR1 | |
| SCHEMBL19754406 | 0.75 | SMN1; SMN2 (0.43) | LMNAALDH1A1RGS4RGS8ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150111978-A1 | METHOD OF FORMING DUAL CURABLE POLYMER COMPOSITIONS | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2015-04-23 | — | — | US | disclosed |