Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betamethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 7/20 | 0.90 |
| ▸ | PGR | P06401 | 5/20 | 0.90 |
| ▸ | MAPT | P10636 | 3/20 | 0.90 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.90 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.90 |
| ▸ | DRD2 | P14416 | 1/20 | 0.90 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | USP2 | O75604 | 5/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | MLNR | O43193 | 1/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.76 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betamethasone Dipropionate SCHEMBL3836657 | 0.99 | NR3C1 (0.90) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL8584606 | 0.99 | NR3C1 (0.90) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL1479319 | 0.98 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL16213556 | 0.98 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL8419 | 0.98 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL11064031 | 0.96 | NR3C1 (0.86) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL1658520 | 0.96 | NR3C1 (0.88) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL10013893 | 0.95 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL9768468 | 0.95 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL11429865 | 0.95 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041906-A1 | METHOD FOR THE PRECIPITATION OF ORGANIC COMPOUNDS | FUJI-FILM MANUFACTURING EUROPE B.V. | 2010-02-18 | — | — | US | claimed |
| EP-1976608-A1 | METHOD FOR THE PRECIPITATION OF ORGANIC COMPOUNDS | FUJIFILM Manufacturing Europe B.V. (NL) | 2008-10-08 | — | — | EP | claimed |
| WO-2007086735-A1 | METHOD FOR THE PRECIPITATION OF ORGANIC COMPOUNDS | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2007-08-02 | — | — | WO | claimed |
| US-20250312425-A1 | COMPOSITIONS AND METHODS COMPRISING ADA-1 FOR WOUND HEALING AND VACCINE ENHANCEMENT | UNIV DREXEL (US) | 2025-10-09 | — | — | US | disclosed |
| US-20240197751-A1 | Pharmaceutical composition and use thereof | BARNAS, ARIAN JANKUR CAN (AT) | 2024-06-20 | — | — | US | disclosed |
| US-11992484-B2 | Analgesic formulations and methods for reduced postoperative nausea and vomiting and enhanced postoperative pain relief | HUTCHISON HEALTH, LLC (US) | 2024-05-28 | — | — | US | disclosed |
| US-11992485-B2 | Analgesic formulations and methods for reduced postoperative nausea and vomiting and enhanced postoperative pain relief | HUTCHISON HEALTH, LLC (US) | 2024-05-28 | — | — | US | disclosed |
| US-11969432-B2 | Pharmaceutical composition and use thereof | BARNAS, ARIAN JANKUR CAN (AT) | 2024-04-30 | — | — | US | disclosed |
| US-20240115560-A1 | SYNERGISTIC MULTIMODAL OPIOID FREE ANALGESIC FORMULATION AND METHODS FOR REDUCED POSTOPERATIVE NAUSEA AND VOMITING, INFLAMMATION, AND ENHANCED POSTOPERATIVE PAIN RELIEF | HUTCHISON HEALTH, LLC | 2024-04-11 | — | — | US | disclosed |
| US-20240115561-A1 | SYNERGISTIC MULTIMODAL OPIOID FREE ANALGESIC FORMULATION AND METHODS FOR REDUCED POSTOPERATIVE NAUSEA AND VOMITING, INFLAMMATION, AND ENHANCED POSTOPERATIVE PAIN RELIEF | HUTCHISON HEALTH, LLC | 2024-04-11 | — | — | US | disclosed |
| US-20230218601-A1 | ANALGESIC FORMULATIONS AND METHODS FOR REDUCED POSTOPERATIVE NAUSEA AND VOMITING AND ENHANCED POSTOPERATIVE PAIN RELIEF | HUTCHISON HEALTH, LLC | 2023-07-13 | — | — | US | disclosed |
| WO-2007119213-A2 | A CULTURE MEDIUM AND PHARMACEUTICAL COMPOSITION FOR REGENERATING CARTILAGE TISSUE, A METHOD, USES AND PRODUCTS RELATED THERETO | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007086735-A1 | METHOD FOR THE PRECIPITATION OF ORGANIC COMPOUNDS | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2006135602-A2 | HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS | UNIVERSITY OF ROCHESTER (US) | 2006-12-21 | — | — | WO | disclosed |
| US-6806253-B2 | THERAPEUTIC AND PREVENTIVE ANTI-BACTERIAL VACCINE COMPLEX | TOROSSIAN FERNAND NARBEY (FR) | 2004-10-19 | — | — | US | disclosed |
| US-20020032152-A1 | ANTI-HELICOBACTER VACCINE COMPLEX | TOROSSIAN FERNAND NARBEY (FR) | 2002-03-14 | — | — | US | disclosed |
| EP-0343268-A1 | Pharmaceutical composition and process for preparing the same | BIOGAL GYOGYSZERGYAR (HU) | 1989-11-29 | — | — | EP | disclosed |
| US-4406883-A | SHAPES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-09-27 | — | — | US | disclosed |
| US-4292300-A | METHYL CELLULOSE, WATER, DRUG | INVERESK RESEARCH INTERNATIONAL (GB) | 1981-09-29 | — | — | US | disclosed |