Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betamethasone Dipropionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 7/20 | 0.91 |
| ▸ | PGR | P06401 | 5/20 | 0.91 |
| ▸ | MAPT | P10636 | 3/20 | 0.91 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.91 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.91 |
| ▸ | DRD2 | P14416 | 1/20 | 0.91 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.77 |
| ▸ | USP2 | O75604 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | MLNR | O43193 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.77 |
| ▸ | PPARG | P37231 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.74 |
| ▸ | AR | P10275 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betamethasone Dipropionate SCHEMBL16213556 | 1.00 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL1479319 | 1.00 | NR3C1 (0.91) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL1658520 | 0.98 | NR3C1 (0.88) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL8584606 | 0.98 | NR3C1 (0.90) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL2271231 | 0.98 | NR3C1 (0.90) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL3836657 | 0.98 | NR3C1 (0.90) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL11064031 | 0.96 | NR3C1 (0.86) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL9768468 | 0.96 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL11429865 | 0.96 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 | |
| Betamethasone Dipropionate SCHEMBL10013893 | 0.96 | NR3C1 (1.00) | NR3C1PGRMAPTNR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8930 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820479-B1 | METHODS TO REDUCE COMPLICATIONS OF INTRA-ARTICULAR STEROID | TAIWAN LIPOSOME CO LTD (TW) | 2026-03-11 | — | — | EP | claimed |
| US-12514820-B2 | Pharmaceutical composition of intra-articular corticosteroid for pain control | TAIWAN LIPOSOME CO., LTD. (TW) | 2026-01-06 | — | — | US | claimed |
| EP-4301343-B1 | PHARMACEUTICAL COMPOSITIONS WITH REDUCED SIDE EFFECT AND METHODS OF USING THE SAME | TLC BIOPHARMACEUTICALS INC (US) | 2025-11-19 | — | — | EP | claimed |
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| US-12364682-B2 | Use of tegaserod in preparation of anti-tumor drug | QINGDAO HAIJI BIOMEDICINE CO., LTD. (CN) | 2025-07-22 | — | — | US | claimed |
| CN-120022371-A | Organic molecule self-assembly body used as material-free drug carrying system, and preparation method and application thereof | 四川大学华西医院 | 2025-05-23 | — | — | CN | claimed |
| WO-2025096949-A1 | LIPOSOMAL COMPOSITION OF INTRA-ARTICULAR CORTICOSTEROID FOR PAIN CONTROL | TAIWAN LIPOSOME COMPANY, LTD. (CN) | 2025-05-08 | — | — | WO | claimed |
| CN-119868165-A | Preparation method and device of betamethasone sodium phosphate injection | 西安国康瑞金制药有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119780280-A | Method for measuring betamethasone sodium phosphate injection disodium edetate by liquid chromatography | 辰欣药业股份有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-20250059301-A1 | Fusion Protein Construct | NORTHWESTERN UNIVERSITY | 2025-02-20 | — | — | US | claimed |
| WO-1997015298-A1 | COMBINATION OF LTD, RECEPTOR ANTAGONISTS WITH GLUCOCORTICOSTEROIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | claimed |
| US-5624962-A | FOR OPHTHALMIC, DERMATOLOGICAL AND BADY CAVITICAL USE | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | claimed |
| EP-0740528-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1996-11-06 | — | — | EP | claimed |
| EP-0694310-A1 | REVERSIBLE, THERMALLY GELLING WATER-BASE MEDICINAL COMPOSITION | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1996-01-31 | — | — | EP | claimed |
| WO-1995015118-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1995-06-08 | — | — | WO | claimed |
| EP-0259983-B1 | The use of corticosteroids for amelioration or elimination of postoperative pain | CARY GEORGE R JR (US) | 1995-02-15 | — | — | EP | claimed |
| CN-1065996-A | Reduce the method for side reaction of trichosanthes kirilowii protein | SHANGHAI INST ORGANIC CHEM (CN) | 1992-11-11 | — | — | CN | claimed |
| US-4406883-A | SHAPES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-09-27 | — | — | US | claimed |
| US-4292300-A | METHYL CELLULOSE, WATER, DRUG | INVERESK RESEARCH INTERNATIONAL (GB) | 1981-09-29 | — | — | US | claimed |
| US-4265875-A | HYDROXYPROPYL METHYL CELLULOSE | INVERESK RESEARCH INTERNATIONAL (GB) | 1981-05-05 | — | — | US | claimed |