4-Hydroxyacetophenone

4-Hydroxyacetophenone

SCHEMBL22717023

CC(=O)c1ccc(O)cc1.CC(=O)c1cccc(O)c1.O=c1c2ccccc2sc2ccc(O)cc12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.46
ALDH1A1 P00352 5/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HCRTR1 O43613 2/20 0.46
POLB P06746 2/20 0.46
LMNA P02545 1/20 0.46
RAB9A P51151 4/20 0.45
KDM4E B2RXH2 3/20 0.45
NPC1 O15118 3/20 0.45
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TRPV1 Q8NER1 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
HPGD P15428 2/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42
RELA Q04206 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614835 0.84 KDM4E (0.57) MAPTALDH1A1L3MBTL1HCRTR1POLB
SCHEMBL29518570 0.81 KDM4E (0.64) MAPTALDH1A1L3MBTL1HCRTR1POLB
SCHEMBL44047 0.81 KDM4E (0.64) MAPTALDH1A1L3MBTL1HCRTR1POLB
SCHEMBL22717024 0.80 MAOA (0.44) MAPTALDH1A1L3MBTL1HCRTR1POLB
Acetophenone SCHEMBL10711555 0.80 MAPT (0.49) MAPTALDH1A1L3MBTL1HCRTR1POLB
Acetophenone SCHEMBL28225737 0.77 KDM4E (0.73) MAPTALDH1A1L3MBTL1HCRTR1POLB
SCHEMBL11661517 0.76 ALDH1A1 (0.58) MAPTALDH1A1L3MBTL1HCRTR1POLB
Acetophenone SCHEMBL28215843 0.75 MAPT (0.47) MAPTALDH1A1L3MBTL1HCRTR1POLB
SCHEMBL7915404 0.74 CYP1A2 (0.60) MAPTALDH1A1L3MBTL1RAB9ANPC1
Phenol SCHEMBL27962832 0.73 MAOA (0.59) MAPTALDH1A1L3MBTL1HCRTR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020243559-A1 PRESSURE SENSITIVE ADHESIVES MADE FROM UV CURING OF PLANT OIL-BASED POLYESTERS OREGON STATE UNIVERSITY (US) 2020-12-03 WO disclosed