Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271846 | 1.00 | NR4A1 (0.57) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL2273820 | 0.84 | ALDH1A1 (0.56) | SRD5A2ALDH1A1NQO2 | |
| SCHEMBL2273823 | 0.84 | ALDH1A1 (0.56) | SRD5A2ALDH1A1NQO2 | |
| SCHEMBL710589 | 0.81 | NR4A1 (0.49) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL2271311 | 0.79 | MAPT (0.61) | CES2CES1ALDH1A1NQO2 | |
| SCHEMBL2271314 | 0.79 | MAPT (0.61) | CES2CES1ALDH1A1NQO2 | |
| SCHEMBL4901207 | 0.79 | CYP1A2 (0.59) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL4901204 | 0.79 | CYP1A2 (0.59) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL9619495 | 0.79 | MAPT (0.66) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL29089422 | 0.78 | CYP1A1 (0.56) | NR4A1NR4A2NR4A3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218388-A | β-carbonyl olefinic amine compound and as the application preparing antibacterial agents for pathogenic bacteria | UNIV NORTHWEST A&F | 2016-01-06 | — | — | CN | disclosed |
| US-7989633-B2 | 4-Chromenonyl-1,4-dihydropyridines and their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-02 | — | — | US | disclosed |
| US-20100022484-A1 | 4-Chromenonyl-1,4-dihydropyridines and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022484-A1 | 4-Chromenonyl-1,4-dihydropyridines and their use | RYR1, RYR2, CACNA1S | NR4A1 235/4885NR4A2 328/4885NR4A3 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.