Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043625 | 0.80 | ALDH1A1 (0.58) | MAPTMEN1KMT2ACES2MAOB | |
| SCHEMBL6139630 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2ACES2CES1 | |
| SCHEMBL10869367 | 0.79 | NR4A1 (0.43) | MAPTMEN1KMT2ANR4A1NR4A2 | |
| SCHEMBL2271850 | 0.79 | NR4A1 (0.57) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL2271846 | 0.79 | NR4A1 (0.57) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL13864065 | 0.78 | NFE2L2 (0.59) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL11625967 | 0.78 | CES2 (0.55) | NR4A1NR4A2NR4A3CES2CES1 | |
| Methylsulfanylmethane SCHEMBL28763708 | 0.77 | CES2 (0.50) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL7228800 | 0.77 | CES2 (0.59) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL28474124 | 0.77 | MEN1 (0.74) | MAPTMEN1KMT2ASRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263958-B1 | 4-SUBSTITUTED-2,6-DIPHENYLPYRIDINE DERIVATIVES, USE THEREOF, PRODUCTION OF THE SAME, CHEMICAL INTERMEDIATES THEREIN AND HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4849011-A | 4-substituted-2,6-diphenylpyridine compounds and herbicide containing the same as an active ingredient | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1989-07-18 | — | — | US | disclosed |