Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238281 | 0.92 | ELANE (0.56) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL7100380 | 0.92 | ELANE (0.56) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL496910 | 0.87 | ELANE (0.60) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL899150 | 0.87 | MEN1 (0.68) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL15315044 | 0.84 | ELANE (0.53) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL8581315 | 0.82 | MEN1 (0.63) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL23198953 | 0.82 | MAPT (0.53) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL8545502 | 0.82 | MAPT (0.53) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL9510889 | 0.80 | MEN1 (0.55) | ELANEMEN1KMT2AMAPTMAOA | |
| SCHEMBL3174840 | 0.77 | BCL2 (0.71) | ELANEMEN1KMT2AMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888670-A1 | DRUG FOR TREATING LEUKOPENIA, PREPARATION METHOD THEREFOR AND USE THEREOF | Hubei Monyan Pharmaceutical Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020238420-A1 | DRUG FOR TREATING LEUKOPENIA, PREPARATION METHOD THEREFOR AND USE THEREOF | 湖北梦阳药业股份有限公司 | 2020-12-03 | — | — | WO | disclosed |