Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198953 | 0.87 | MAPT (0.53) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL5075855 | 0.86 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL29360530 | 0.86 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL9131211 | 0.86 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL28019688 | 0.82 | MAPT (0.55) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL22719979 | 0.82 | ELANE (0.56) | MAPTALDH1A1KMT2AL3MBTL1RAB9A | |
| SCHEMBL22799167 | 0.81 | LDHA (0.49) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL15315053 | 0.81 | MAPT (0.54) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL8756313 | 0.79 | MAPT (0.55) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL29450065 | 0.79 | MAPT (0.53) | MAPTALDH1A1KMT2AL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725778-A4 | RECOMBINANT PRODUCTION OF NOVEL POLYKETIDES | UNIV LELAND STANFORD JUNIOR (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0725778-A1 | RECOMBINANT PRODUCTION OF NOVEL POLYKETIDES | THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995008548-A1 | RECOMBINANT PRODUCTION OF NOVEL POLYKETIDES | THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1995-03-30 | — | — | WO | disclosed |