Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17995727 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL9355722 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL28897058 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL3336310 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL11646248 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL26622691 | 0.99 | TSHR (0.55) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL9356169 | 0.99 | TSHR (0.55) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL6426863 | 0.93 | TSHR (0.53) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL18817715 | 0.93 | ALDH1A1 (0.57) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL28982972 | 0.93 | ALDH1A1 (0.57) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237772-A1 | INDUSTRIAL PREPARATION METHOD FOR ZIEGLER-NATTA CATALYST | 国家能源集团宁夏煤业有限责任公司 | 2020-12-03 | — | — | WO | disclosed |