SCHEMBL6426863

SCHEMBL6426863

CCCCOC(=O)c1ccc(C(=O)O)cc1CCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPK1 P28482 3/20 0.51
CYP3A4 P08684 3/20 0.51
TP53 P04637 2/20 0.51
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.50
ESR1 P03372 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2D6 P10635 1/20 0.50
NR1H2 P55055 1/20 0.50
RNASEL Q05823 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP2C9 P11712 1/20 0.49
PDE4D Q08499 1/20 0.49
PLA2G4B P0C869 1/20 0.48
NPC1 O15118 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9356169 0.95 TSHR (0.55) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL26622691 0.95 TSHR (0.55) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL11646248 0.93 TSHR (0.56) TSHRMAPK1CYP3A4TP53ALDH1A1
SCHEMBL28897058 0.93 TSHR (0.56) TSHRMAPK1CYP3A4TP53ALDH1A1
SCHEMBL22719984 0.93 TSHR (0.56) TSHRMAPK1CYP3A4TP53ALDH1A1
SCHEMBL17995727 0.93 TSHR (0.56) TSHRMAPK1CYP3A4TP53ALDH1A1
SCHEMBL9355722 0.93 TSHR (0.56) TSHRMAPK1CYP3A4TP53ALDH1A1
SCHEMBL3336310 0.93 TSHR (0.56) TSHRMAPK1CYP3A4TP53ALDH1A1
SCHEMBL20334968 0.88 RARB (0.48) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL1332645 0.87 TSHR (0.59) TSHRMAPK1CYP3A4TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808101-B2 Composition for hydrolytic stabilization of polyester CLARIANT PLASTICS & COATINGS LTD (CH) 2020-10-20 US claimed
WO-2016089808-A1 PROCESSES AND CATALYSTS FOR CONVERSION OF 2,5-DIMETHYLFURAN DERIVATIVES TO TEREPHTHALATES UOP LLC (US) 2016-06-09 WO disclosed
US-9321714-B1 Processes and catalysts for conversion of 2,5-dimethylfuran derivatives to terephthalate UOP LLC (US) 2016-04-26 US disclosed
US-6846619-B2 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. (JP) 2005-01-25 US disclosed
EP-1243437-B1 Leuco dye dispersion liquid and thermosensitive recording material using the same RICOH KK (JP) 2004-11-17 EP disclosed
US-20030060366-A1 Dye dispersion liquid and thermosensitive recording material using the same RICOH COMPANY, LTD. 2003-03-27 US disclosed
EP-1243437-A1 Leuco dye dispersion liquid and thermosensitive recording material using the same Ricoh Company, Ltd. (JP) 2002-09-25 EP disclosed
US-5310641-A Inner core, plurlity of outer shells substantially containing silver bromide or iodobromide; high speed, graininess, sharp, low fog density; astronomical, indoor, sports photography KONICA CORPORATION (JP) 1994-05-10 US disclosed
EP-0202784-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1991-09-25 EP disclosed
EP-0202784-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10808101-B2 Composition for hydrolytic stabilization of polyester C1R, CEL, CMA1 TSHR 4571/4885TDP1 300/4885L3MBTL1 2157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.