Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2401416 | 0.83 | HPGD (0.71) | HPGDHTTPOLBKDM4ETP53 | |
| SCHEMBL28221148 | 0.82 | HPGD (0.69) | HPGDHTTPOLBKDM4ETP53 | |
| SCHEMBL19747178 | 0.82 | HPGD (0.69) | HPGDHTTPOLBKDM4ETP53 | |
| SCHEMBL12907922 | 0.80 | KDM4E (0.70) | HPGDHTTPOLBKDM4ETP53 | |
| SCHEMBL4521778 | 0.78 | GAA (0.64) | HPGDHTTPOLBKDM4ETP53 | |
| SCHEMBL31267447 | 0.78 | ALDH1A1 (0.68) | HPGDHTTKDM4ETP53HSD17B10 | |
| SCHEMBL2234130 | 0.78 | HPGD (1.00) | HPGDHTTPOLBPKMALDH1A1 | |
| SCHEMBL29508722 | 0.77 | HPGD (0.79) | HPGDHTTKDM4ETP53HSD17B10 | |
| SCHEMBL5551614 | 0.77 | HPGD (0.74) | HPGDHTTPOLBTSHRPKM | |
| SCHEMBL2319467 | 0.77 | HPGD (0.64) | HPGDHTTPOLBKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661459-A | 1,2, 3-Benzotriazine-4 (3H) -one seleno compound and preparation method and application thereof | 赣南师范大学 | 2025-03-21 | — | — | CN | disclosed |
| WO-2020239050-A1 | 2-(2-CHLORO-4-METHYLPHENYL)QUINAZOLINE-4(3H)-KETONE COMPOUND AND MEDICAL USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-12-03 | — | — | WO | disclosed |
| CN-110041273-B | 2- (2-chloro-4-methylphenyl) quinazoline-4 (3H) -ketone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-20 | — | — | CN | disclosed |
| CN-110041273-A | 2- (the chloro- 4- aminomethyl phenyl of 2-) quinazoline -4 (3H) -one class compound and its medical usage | 中国人民解放军军事科学院军事医学研究院 | 2019-07-23 | — | — | CN | disclosed |