Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470076 | 0.79 | TBK1 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL1470077 | 0.79 | TBK1 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL22724543 | 0.78 | SETD7 (0.46) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL30957838 | 0.78 | SETD7 (0.46) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL27283617 | 0.77 | ABCB1 (0.42) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL21566123 | 0.77 | ABCB1 (0.42) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL30943543 | 0.77 | ABCB1 (0.42) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL21846846 | 0.75 | MEN1 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL24492752 | 0.75 | GPR119 (0.53) | GPR119SMARCA2SMARCA4PBRM1TBK1 | |
| SCHEMBL28382638 | 0.75 | TBK1 (0.43) | GPR119SMARCA2SMARCA4PBRM1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |