Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.51 |
| ▸ | LPL | P06858 | 8/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25799122 | 0.88 | LIPG (0.55) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL22685318 | 0.85 | LIPG (0.51) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL27254964 | 0.84 | LIPG (0.66) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL22065319 | 0.84 | LIPG (0.48) | LIPGLPLIRAK4ESR2PRMT5 | |
| SCHEMBL22720362 | 0.83 | LIPG (0.49) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL24377085 | 0.82 | LIPG (0.63) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL25799140 | 0.82 | LIPG (0.66) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL27254806 | 0.81 | LIPG (0.61) | LIPGLPLIRAK4PRMT5WDR77 | |
| SCHEMBL31069015 | 0.80 | LIPG (0.60) | LIPGLPL | |
| SCHEMBL190941 | 0.80 | LIPG (0.60) | LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239123-A1 | AROMATIC HETEROCYCLIC DERIVATIVE MODULATOR AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-12-03 | — | — | WO | disclosed |