Formic Acid

Formic Acid

SCHEMBL22720642

C=CC(=O)OCCOC(=O)c1ccccc1C(=O)OCCOC(=O)C=C.O=CO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.57
TSHR P16473 12/20 0.54
CYP3A4 P08684 4/20 0.54
ALDH1A1 P00352 9/20 0.51
TDP1 Q9NUW8 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
TP53 P04637 4/20 0.48
HSD17B10 Q99714 4/20 0.48
HIF1A Q16665 3/20 0.48
MAPK1 P28482 2/20 0.47
LMNA P02545 1/20 0.46
NPC1 O15118 3/20 0.43
HPGD P15428 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
GLA P06280 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL228020 0.95 THRB (0.62) THRBTSHRCYP3A4ALDH1A1TDP1
Formic Acid SCHEMBL22720643 0.94 THRB (0.55) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL9466853 0.90 TSHR (0.63) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL29906120 0.89 TSHR (0.61) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL67954 0.89 THRB (0.55) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL301415 0.89 TSHR (0.61) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL30198617 0.89 THRB (0.59) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL67527 0.89 THRB (0.59) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL7115632 0.88 TSHR (0.62) THRBTSHRCYP3A4ALDH1A1TDP1
SCHEMBL1110904 0.88 TSHR (0.59) THRBTSHRCYP3A4ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020238862-A1 FLUORENE INITIATOR, PHOTOCURABLE COMPOSITION COMPRISING SAME, AND APPLICATION THEREOF 常州强力先端电子材料有限公司 2020-12-03 WO disclosed