SCHEMBL2272067

SCHEMBL2272067

[SiH3]CCC(Cl)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
HRH1 P35367 7/20 0.39
HIF1A Q16665 1/20 0.39
RIPK1 Q13546 2/20 0.38
HTR2A P28223 6/20 0.37
TAAR1 Q96RJ0 1/20 0.37
CACNA1F O60840 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
ADRA2B P18089 1/20 0.35
CHRM3 P20309 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRK1 P41145 1/20 0.35
CACNA1D Q01668 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 1/20 0.35
CACNA1S Q13698 1/20 0.35
CACNA1C Q13936 1/20 0.35
SCN5A Q14524 1/20 0.35
DPP4 P27487 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22042229 0.85 TSHR (0.55) TSHRHRH1HIF1AHTR2ATAAR1
SCHEMBL22042223 0.80 TSHR (0.50) TSHRHRH1HIF1AHTR2ATAAR1
SCHEMBL3218900 0.78 TSHR (0.48) TSHRHRH1HIF1AHTR2ATAAR1
SCHEMBL863751 0.77 HRH1 (0.56) HRH1RIPK1HTR2ATAAR1CHRM2
SCHEMBL15562978 0.76 TSHR (0.46) TSHRHRH1HTR2ATAAR1DPP4
SCHEMBL8110947 0.76 TSHR (0.46) TSHRHRH1HTR2ATAAR1DPP4
SCHEMBL7982428 0.76 TRPA1 (0.48) TSHRHRH1RIPK1HTR2ATAAR1
SCHEMBL4897348 0.76 TSHR (0.46) TSHRHRH1HIF1AHTR2ATAAR1
SCHEMBL4377946 0.76 HRH1 (0.62) TSHRHRH1HTR2ATAAR1SLC6A3
SCHEMBL2239367 0.76 TSHR (0.46) TSHRHRH1RIPK1HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104609771-B Warm-mixing reclaiming agent and preparation method thereof 江苏苏博特新材料股份有限公司 2017-04-12 CN disclosed
CN-104609771-A Warm-mixing reclaiming agent and preparation method thereof JIANGSU SUBOTE NEW MAT CO LTD 2015-05-13 CN disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed