Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4374017 | 0.98 | HRH1 (0.60) | HRH1HTR2ATAAR1TSHRCYP1A2 | |
| SCHEMBL9198696 | 0.86 | HRH1 (0.65) | HRH1HTR2ATAAR1TSHRCYP1A2 | |
| SCHEMBL22042229 | 0.85 | TSHR (0.55) | HRH1HTR2ATAAR1TSHRDPP4 | |
| SCHEMBL28527237 | 0.80 | TAAR1 (0.59) | HRH1HTR2ATAAR1TSHRCYP1A2 | |
| SCHEMBL22042223 | 0.80 | TSHR (0.50) | HRH1HTR2ATAAR1TSHRDPP4 | |
| SCHEMBL3406287 | 0.80 | TAAR1 (0.59) | HRH1HTR2ATAAR1TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL8120982 | 0.78 | TAAR1 (0.56) | HRH1HTR2ATAAR1TSHRSLC6A4 | |
| SCHEMBL3218900 | 0.78 | TSHR (0.48) | HRH1HTR2ATAAR1TSHRDPP4 | |
| SCHEMBL13639028 | 0.77 | HTR2A (0.43) | HRH1HTR2ATAAR1TSHRCYP1A2 | |
| SCHEMBL158098 | 0.77 | HRH1 (1.00) | HRH1HTR2ATAAR1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153948-A | By using acid clean, disinfection and the bactericidal composition of the reduction atomization of high molecular weight water-in-oil emulsion polymer | 埃科莱布美国股份有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-110392528-A | The dangerous disinfectant and fungicide of sucking is reduced by heavy polymer | 埃科莱布美国股份有限公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110172861-A | A kind of no chlorine wet strength agent and preparation method thereof | 浙江恒达新材料股份有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-109153947-A | By using the alkalinity and neutral cleaning, disinfection and bactericidal composition of the reduction atomization of high molecular weight water-in-oil emulsion polymer | 埃科莱布美国股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-109153948-A | By using acid clean, disinfection and the bactericidal composition of the reduction atomization of high molecular weight water-in-oil emulsion polymer | 埃科莱布美国股份有限公司 | 2019-01-04 | — | — | CN | disclosed |
| US-9604906-B2 | Process for the preparation of 3-aryloxy-3-phenylpropylamine and salt thereof | ZCL CHEMICALS LIMITED (IN) | 2017-03-28 | — | — | US | disclosed |
| CN-106320075-A | Internal sizing agent emulsion and preparation method and application of same | 上海东升新材料有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-106256955-A | A kind of plasm-glue-blending agent emulsion and its preparation method and application | 上海东升新材料有限公司 | 2016-12-28 | — | — | CN | disclosed |
| US-20160107983-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 3-ARYLOXY-3-PHENYLPROPYLAMINE AND SALT THEREOF | COHANCE LIFESCIENCES LIMITED (IN) | 2016-04-21 | — | — | US | disclosed |
| WO-2015001565-A2 | \"AN IMPROVED PROCESS FOR THE PREPARATION OF 3-ARYLOXY-3- PHENYLPROPYLAMINE AND SALT THEREOF\ | ZCL CHEMICALS LIMITED (IN) | 2015-01-08 | — | — | WO | disclosed |
| WO-2009141833-A2 | AN IMPROVED PROCESS FOR SYNTHESIZING HIGHLY PURE ATOMOXETINE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | disclosed |
| WO-2008062473-A1 | PROCESS FOR PREPARING ATOMOXETINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008026227-A2 | A PROCESS FOR THE PREPARATION OF ATOMOXETINE HYDROCHLORIDE | MATRIX LABORATORIES LTD (IN) | 2008-03-06 | — | — | WO | disclosed |
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-01-03 | — | — | US | disclosed |
| EP-1794112-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | Dr. Reddy's Laboratories Ltd. (IN) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037055-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-06 | — | — | WO | disclosed |
| WO-2006009884-A1 | 3-ARYLOXY-3-ARYLPROPYLAMINE SYNTHESIS | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | SLC6A2, SLC6A4, SLC6A3 | HRH1 3664/4885HTR2A 11/4885TAAR1 121/4885 |
| US-20160107983-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 3-ARYLOXY-3-PHENYLPROPYLAMINE AND SALT THEREOF | PAH, TYR, NAT1 | HRH1 630/4885HTR2A 442/4885TAAR1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.