Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20556335 | 0.89 | MAPT (0.55) | MAPTTSHRTP53THRB | |
| SCHEMBL4055639 | 0.89 | MAPT (0.50) | MAPTSOD1CYP2C19HRH3TP53 | |
| SCHEMBL10994640 | 0.87 | MAPT (0.57) | MAPTSOD1CYP2C19HRH3TSHR | |
| SCHEMBL17164040 | 0.83 | MAPT (0.53) | MAPTSOD1CYP2C19TSHR | |
| SCHEMBL5978753 | 0.83 | MAPT (0.53) | MAPTSOD1CYP2C19HRH3TSHR | |
| SCHEMBL5724934 | 0.83 | MAPT (0.53) | MAPTSOD1CYP2C19TSHRMAPK1 | |
| SCHEMBL8297095 | 0.83 | MAPT (0.59) | MAPTTSHRTHRB | |
| SCHEMBL25162165 | 0.80 | MAPT (0.61) | MAPTSOD1CYP2C19TSHRMAPK1 | |
| SCHEMBL10359368 | 0.80 | MAPT (0.55) | MAPTSOD1CYP2C19TSHRTP53 | |
| SCHEMBL5043400 | 0.80 | MAPT (0.55) | MAPTSOD1CYP2C19TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765263-B1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765263-B1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-7662869-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662869-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662869-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | TAS2R41, TAS2R42, TAS1R1 | MAPT 3226/4885SOD1 973/4885CYP2C19 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.