Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720995 | 0.84 | MEN1 (0.60) | MEN1KMT2APDCD1LG2CD274HSD11B1 | |
| SCHEMBL11551138 | 0.78 | LMNA (0.42) | MEN1KMT2ALMNAPOLBTUBB4A | |
| SCHEMBL19689047 | 0.78 | MEN1 (0.59) | MEN1KMT2APOLBPDCD1LG2CD274 | |
| SCHEMBL24168763 | 0.76 | MEN1 (0.54) | MEN1KMT2A | |
| SCHEMBL31472389 | 0.76 | MEN1 (0.89) | MEN1KMT2AKDM4E | |
| SCHEMBL27343153 | 0.76 | LMNA (0.41) | MEN1KMT2ALMNAPOLBTUBB4A | |
| SCHEMBL21491464 | 0.76 | MEN1 (0.89) | MEN1KMT2AKDM4E | |
| SCHEMBL21516972 | 0.76 | MEN1 (0.69) | MEN1KMT2A | |
| SCHEMBL29456488 | 0.76 | MEN1 (0.69) | MEN1KMT2A | |
| SCHEMBL16610538 | 0.75 | MEN1 (0.73) | MEN1KMT2APDCD1LG2CD274HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230554-C | Method for enzymatic enantiomer-separation of 3(R)-and 3(S)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridine or its carboxylic acid esters | AWENTIS MEDICINE DEUTSCHE AG (DE) | 2005-12-07 | — | — | CN | disclosed |
| CN-1137096-C | Process for the preparation of (-) cis-3-hydroxy-1-methyl-4- (2,4, 6-trimethoxyphenyl) -piperidine | ���ĵ�˹ҩ��¹�����˾ | 2004-02-04 | — | — | CN | disclosed |
| CN-1292034-A | Method for the enzymatic separation of enantiomers of 3 -and 3(S) -hydroxy-1-methyl-4- (2,4, 6-trimethoxyphenyl) -1, 2,3, 6-tetrahydropyridine or its carboxylic esters | AWENTIS MEDICINE DEUTSCHE AG (DE) | 2001-04-18 | — | — | CN | disclosed |
| CN-1284065-A | Method for producing (-) Cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperidine | AVENTIES PHARMACEUTICAL DEUTSC (DE) | 2001-02-14 | — | — | CN | disclosed |