SCHEMBL21718280

SCHEMBL21718280

c1ccc(-n2c3ccccc3c3cc4c5cccc6c7c8ccccc8ccc7n(c4cc32)c56)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
SIGMAR1 Q99720 1/20 0.31
PTGES O14684 1/20 0.31
JAK2 O60674 1/20 0.30
JAK3 P52333 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
BRCA1 P38398 1/20 0.30
HSD17B10 Q99714 1/20 0.30
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30
PRSS1 P07477 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24026562 0.93 KDM4E (0.40) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL22722284 0.89 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL25965206 0.89 KDM4E (0.44) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL21717569 0.88 KDM4E (0.49) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL22722264 0.88 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL24026563 0.88 KDM4E (0.40) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL21717590 0.87 KDM4E (0.47) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL24026662 0.87 KDM4E (0.47) KDM4EATML3MBTL1KMT2AALDH1A1
SCHEMBL24026861 0.87 ALDH1A1 (0.35) ATML3MBTL1ALDH1A1TSHRHSD17B10
SCHEMBL21718155 0.87 KDM4E (0.60) KDM4EATML3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO.,LTD. (JP) 2023-12-05 US disclosed
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO.,LTD. (JP) 2023-12-05 US disclosed
US-20200266361-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-08-20 US disclosed
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839153-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device RER1, RPS19, RPL19 KDM4E 1641/4885ATM 2012/4885L3MBTL1 210/4885
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ESR2 KDM4E 2210/4885ATM 3221/4885L3MBTL1 683/4885
US-20200266361-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE RER1, RPS19, RPL19 KDM4E 1641/4885ATM 2012/4885L3MBTL1 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.