Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025339 | 1.00 | FDPS (0.47) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL18760169 | 0.83 | FFAR1 (0.54) | FDPSSMPD1GGPS1 | |
| SCHEMBL24013318 | 0.82 | FAAH (0.43) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL22380833 | 0.82 | SOAT1 (0.50) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL22380733 | 0.82 | SOAT1 (0.50) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL19176750 | 0.82 | SOAT1 (0.50) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL22380821 | 0.82 | SOAT1 (0.50) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL19861311 | 0.81 | TDP1 (0.56) | — | |
| SCHEMBL22877776 | 0.81 | TDP1 (0.56) | — | |
| SCHEMBL18852720 | 0.81 | TDP1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702416-B2 | 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins | INCYTE CORPORATION (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230041563-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES OR SALTS THEREOF, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND USES THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| US-20210300925-A1 | 1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS | INCYTE CORPORATION | 2021-09-30 | — | — | US | disclosed |
| US-11059821-B2 | 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins | INCYTE CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200377502-A1 | 1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS | INCYTE CORPORATION | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377502-A1 | 1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS | BRD3, BRD1, BRD2 | FDPS 4056/4885SMPD1 4080/4885GGPS1 2709/4885 |
| US-20230041563-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES OR SALTS THEREOF, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND USES THEREOF | CYP2B6, CBR3, CYP2A6 | FDPS 3772/4885SMPD1 4348/4885GGPS1 4194/4885 |
| US-11059821-B2 | 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins | BRD3, BRD1, BRD2 | FDPS 4056/4885SMPD1 4080/4885GGPS1 2709/4885 |
| US-11702416-B2 | 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins | BRD3, BRD1, BRD2 | FDPS 4056/4885SMPD1 4080/4885GGPS1 2709/4885 |
| US-20210300925-A1 | 1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS | BRD3, BRD1, BRD2 | FDPS 4056/4885SMPD1 4080/4885GGPS1 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.