Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413341 | 0.83 | APEX1 (1.00) | APEX1KMT2ALMNANPSR1TSHR | |
| SCHEMBL17072393 | 0.80 | APEX1 (0.71) | APEX1KMT2ALMNAGABRR1THRB | |
| SCHEMBL9271184 | 0.76 | APEX1 (0.74) | APEX1KMT2ALMNANPSR1TSHR | |
| SCHEMBL7131000 | 0.76 | APEX1 (0.74) | APEX1KMT2ALMNATSHRHDAC3 | |
| SCHEMBL11696751 | 0.74 | APEX1 (0.79) | APEX1KMT2ALMNANPSR1TSHR | |
| Hydrochloric Acid SCHEMBL10583773 | 0.74 | APEX1 (0.70) | APEX1KMT2ALMNATSHRHDAC3 | |
| SCHEMBL1463490 | 0.72 | — | — | |
| SCHEMBL1200576 | 0.72 | APEX1 (0.75) | APEX1KMT2ALMNATSHRHDAC3 | |
| SCHEMBL11335285 | 0.72 | APEX1 (0.75) | APEX1KMT2ALMNANPSR1TSHR | |
| Hydrochloric Acid SCHEMBL10537638 | 0.70 | APEX1 (0.71) | APEX1KMT2ALMNABLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3744729-B1 | PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES | SEDERMA SA (FR) | 2023-03-01 | — | — | EP | disclosed |
| EP-3744729-A1 | COMPOUNDS, IN PARTICULAR PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES | SEDERMA (FR) | 2020-12-02 | — | — | EP | disclosed |