SCHEMBL4413341

SCHEMBL4413341

O=C(O)CCS(=O)(=O)CCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 2/20 1.00
LMNA P02545 5/20 0.50
EGLN1 Q9GZT9 2/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
SUCNR1 Q9BXA5 1/20 0.50
KMT2A Q03164 3/20 0.48
POLB P06746 1/20 0.47
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.44
TSHR P16473 2/20 0.42
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42
FFAR3 O14843 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
SLC15A2 Q16348 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11696751 0.89 APEX1 (0.79) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL1200576 0.87 APEX1 (0.75) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL11335285 0.87 APEX1 (0.75) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL7131000 0.85 APEX1 (0.74) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL9271184 0.85 APEX1 (0.74) APEX1LMNAEGLN1ALKBH5SUCNR1
Hydrochloric Acid SCHEMBL10537638 0.84 APEX1 (0.71) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL17072393 0.84 APEX1 (0.71) APEX1LMNAEGLN1ALKBH5SUCNR1
Hydrochloric Acid SCHEMBL10583773 0.83 APEX1 (0.70) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL22726953 0.83 APEX1 (0.70) APEX1LMNAEGLN1ALKBH5SUCNR1
SCHEMBL5127159 0.83 APEX1 (0.68) APEX1LMNAKMT2APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100589903-C Preparation method of uncoated nanometer metal oxide powder UNIV DALIAN TECH 2010-02-17 CN claimed
US-7638053-B2 crosslinked addition-condensation copolymer contains a polyester endcapped with a vinyl polymerized compound such as acrylic acid, methacrylic acid; use in petroleum industry pervaporation technology to reduce energy costs; stability; for separation of aromatic hydrocarbon from aliphatic hydrocarbon GENERAL ELECTRIC COMPANY (US) 2009-12-29 US claimed
CN-100999022-A Preparation method of uncoated nanometer metal oxide powder UNIV DALIAN TECH (CN) 2007-07-18 CN claimed
US-20060289352-A1 Poly(meth)acrylate membranes for separation of hydrocarbon mixtures BL TECHNOLOGIES, INC. 2006-12-28 US claimed
JP-2229150-A None JP disclosed
US-11685809-B2 Phosphorus-containing polymers, and methods of producing thereof NOVOMER, INC. (US) 2023-06-27 US disclosed
US-11685809-B2 Phosphorus-containing polymers, and methods of producing thereof NOVOMER, INC. (US) 2023-06-27 US disclosed
US-11685809-B2 Phosphorus-containing polymers, and methods of producing thereof NOVOMER, INC. (US) 2023-06-27 US disclosed
EP-3768742-A1 SULFUR- AND PHOSPHORUS-CONTAINING POLYMERS, AND METHODS OF PRODUCING THEREOF Novomer, Inc. (US) 2021-01-27 EP disclosed
US-20210009753-A1 SULFUR- AND PHOSPHORUS-CONTAINING POLYMERS, AND METHODS OF PRODUCING THEREOF NOVOMER, INC. 2021-01-14 US disclosed
US-20210009753-A1 SULFUR- AND PHOSPHORUS-CONTAINING POLYMERS, AND METHODS OF PRODUCING THEREOF NOVOMER, INC. 2021-01-14 US disclosed
CN-111954686-A Sulfur-containing polymer and phosphorus-containing polymer, and production method thereof 诺沃梅尔公司 2020-11-17 CN disclosed
US-5023378-A Hypotensive agents, antiischemic agents, urogenital disorders GLAXO GROUP LIMITED (GB) 1991-06-11 US disclosed
EP-0188361-B1 AMINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1991-03-06 EP disclosed
JP-H02229150-A 3,3'-SULFONYL DIPROPIONIC ACID DIALLYL ESTER AND PRODUCTION THEREOF SANKO KAIHATSU KAGAKU KENKYUSHO:KK 1990-09-11 JP disclosed
US-4824591-A BLEACHES, DETERGENTS MONSANTO COMPANY (US) 1989-04-25 US disclosed
US-4758369-A Sulfone peroxycarboxylic acids MONSANTO COMPANY (US) 1988-07-19 US disclosed
EP-0267175-A2 Sulfone peroxycarboxylic acids Monsanto Company (US) 1988-05-11 EP disclosed
EP-0188361-A1 Amine derivatives GLAXO GROUP LIMITED (GB) 1986-07-23 EP disclosed
EP-0021676-B1 3-METHOXY-2-OXOAZETIDINE DERIVATIVES AND THEIR PRODUCTION Takeda Chemical Industries, Ltd. (JP) 1983-09-14 EP disclosed