Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.79 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413341 | 0.89 | APEX1 (1.00) | APEX1CAMK2AKMT2ALMNAALDH1A1 | |
| SCHEMBL17822770 | 0.81 | GPR84 (0.56) | APEX1CAMK2AKMT2ALMNAALDH1A1 | |
| SCHEMBL6223633 | 0.80 | — | — | |
| SCHEMBL505953 | 0.80 | — | — | |
| SCHEMBL1200576 | 0.77 | APEX1 (0.75) | APEX1KMT2ALMNAALDH1A1GPR84 | |
| SCHEMBL13901852 | 0.77 | APEX1 (0.46) | APEX1KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL11335285 | 0.77 | APEX1 (0.75) | APEX1KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL13923318 | 0.77 | APEX1 (0.46) | APEX1KMT2APMP22 | |
| SCHEMBL13901846 | 0.77 | APEX1 (0.46) | APEX1KMT2AALDH1A1HTT | |
| SCHEMBL9271184 | 0.76 | APEX1 (0.74) | APEX1KMT2ALMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046647-A | BETA-SUBSTITUTED, GAMMA-SUBSTITUTED, OR BETA, GAMMA-DISUBSTITUTED SULFONE | M&T CHEMICALS INC. (US) | 1977-09-06 | — | — | US | claimed |
| EP-2030968-B1 | Sulfur-containing compound, method of preparation and pharmaceutical uses thereof | NAT SUN YAT-SEN UNIV (TW) | 2017-02-22 | — | — | EP | disclosed |
| US-9238620-B1 | Pharmaceutical uses of sulfur-containing compound | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2016-01-19 | — | — | US | disclosed |
| US-20160009642-A1 | PHARMACEUTICAL USES OF SULFUR-CONTAINING COMPOUND | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2016-01-14 | — | — | US | disclosed |
| US-8722745-B2 | Sulfur-containing compound, method of preparation and pharmaceutical uses thereof | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2014-05-13 | — | — | US | disclosed |
| US-20130172355-A1 | SULFUR-CONTAINING COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2013-07-04 | — | — | US | disclosed |
| EP-2030968-A2 | Sulfur-containing compound, method of preparation and pharmaceutical uses thereof | National Sun Yat-Sen University (TW) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009642-A1 | PHARMACEUTICAL USES OF SULFUR-CONTAINING COMPOUND | CTH, MPST, CBS | APEX1 2272/4885CAMK2A 3865/4885KMT2A 3793/4885 |
| US-20130172355-A1 | SULFUR-CONTAINING COMPOUND, METHOD OF PREPARATION AND PHARMACEUTICAL USES THEREOF | CBS, SQOR, TST | APEX1 535/4885CAMK2A 3127/4885KMT2A 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.