Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12695291 | 0.84 | ALDH1A1 (0.45) | ALDH1A1GAAL3MBTL1NR3C2AR | |
| SCHEMBL12540480 | 0.80 | ATR (0.42) | ALDH1A1GAAL3MBTL1NR3C2AR | |
| SCHEMBL13331892 | 0.77 | ATR (0.44) | ALDH1A1GAAL3MBTL1NR3C2AR | |
| SCHEMBL13563525 | 0.76 | GAA (0.49) | ALDH1A1GAAL3MBTL1NR3C2AR | |
| SCHEMBL15077819 | 0.75 | IGF1R (0.46) | NR3C2ATRGSK3BDYRK1AIGF1R | |
| SCHEMBL2406509 | 0.75 | NR3C2 (0.47) | NR3C2ATRIGF1RCYP17A1CCR2 | |
| SCHEMBL1940483 | 0.75 | IGF1R (0.48) | NR3C2ATRGSK3BDYRK1AIGF1R | |
| SCHEMBL29575346 | 0.75 | IGF1R (0.48) | NR3C2ATRGSK3BDYRK1AIGF1R | |
| SCHEMBL15354529 | 0.75 | RIOK2 (0.50) | NR3C2ATRGSK3BDYRK1AIGF1R | |
| SCHEMBL29272503 | 0.74 | BRAF (0.44) | ALDH1A1GAAL3MBTL1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976189-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2024-07-03 | — | — | EP | disclosed |
| WO-2020239658-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2020-12-03 | — | — | WO | disclosed |