Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22727569 | 0.91 | TSHR (0.43) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27317243 | 0.75 | TSHR (0.56) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11785050 | 0.73 | TSHR (0.55) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22739361 | 0.71 | TSHR (0.39) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22739243 | 0.69 | TSHR (0.35) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11779300 | 0.69 | TSHR (0.63) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11782048 | 0.68 | TSHR (0.54) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22727452 | 0.67 | TSHR (0.54) | TSHRHPGDCCKBRHSP90AA1HSP90AB1 | |
| SCHEMBL11785578 | 0.66 | SLC6A4 (0.50) | TSHRHPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22739234 | 0.65 | TSHR (0.40) | TSHRHPGDSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243153-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-12-03 | — | — | WO | disclosed |