Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321163 | 0.90 | HDAC3 (0.52) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL27797896 | 0.84 | HDAC3 (0.52) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31644307 | 0.84 | HDAC3 (0.52) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL28375889 | 0.83 | HDAC8 (0.53) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319590 | 0.83 | HDAC3 (0.51) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319639 | 0.81 | HDAC3 (0.49) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319666 | 0.80 | HDAC3 (0.48) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319588 | 0.80 | AR (0.56) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319580 | 0.80 | AR (0.56) | HDAC3HDAC8NCOR2SCDAR | |
| SCHEMBL31319701 | 0.79 | AR (0.48) | HDAC3HDAC8NCOR2SCDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243373-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2020-12-03 | — | — | WO | disclosed |